@Uetam:
I don't know these two games but I assume they are DOS games? Additionally I assume by saying "start the game with desktop icon" you mean starting the game via a desktop icon created by DFR? In this case there should be no difference between starting the game via the desktop icon or via DFR directly. The desktop icon link is only starting DFR and telling it to start the game (nothing else than clicking on the game entry in the DFR games list). So in this case the only difference is the DFR window flickering for a short time before the game is started. DOSBox is a very powerful program allowing to run many DOS games on nearly any graphics card configuration on a modern system, but sometimes there are some problems in some configurations. So if you have problems running a DOS game in DOSBox via DFR (even if the problem only occurs in some situations), you can try changing the graphics settings for the game (see "Graphics card" section in the profile editor).
I can play both games fine starting the main "exe" without DFR.
If you can start the game exe file directly from the Windows explorer without DFR and DOSBox the game is no DOS game. You can also add Windows games to the DFR games list. But in this case DFR is doing nothing more than just starting the exe file so there is no advantage in using DFR before just running the game directly (via the Windows explorer, the start menu etc.).
when I configure a profile game, when I click on the icon folder (for example for select the exe or config file) do nothing.
Sorry, I cannot reproduce this problem (running Windows 7 64 bit, too). At first, I think you mean: When you are clicking the "Select game exe file" button next to the game exe input line on the "Profile" page of the profile editor nothing happens. This would be strange, because DFR is just showing the default Windows file select dialog via the default Windows API function.