The listing for this game is here.

I have tried this game with dosbox 0.61 and the current CVS version, with varying EMS sizes, varying amounts of standard memory free, and XMS disabled.

Upon attempting to run the game:

In the debug log appears the line:
MISC:EMS:Call 5A not supported

This originates from the function "static Bitu INT67_Handler(void)" in src/ints/ems.cpp, which has support for many other EMS calls but not 5A.