Reply 1 of 6, by _Rob
Some additional details as to what your trying to do would have been helpful. I also don't know what this spirometer program is.
If it is trying to communicate to your real COM port (serial port), you need to configure your dosbox config file as follows, assuming your on a Windows system:
That way any program in DOSBox that uses COM1 will use the real COM1 on your Windows PC. This is also mentioned on the Wiki:
Reply 2 of 6, by evasive
Ok this is by far not retro, but windows 10! However: turn off HVCI, some drivers do not like it at all:
https://nakedsecurity.sophos.com/2020/03/09/m … using-problems/
Reply 3 of 6, by d0k
This is a serial port. I have the configuration as mentioned, the software worked, but about a month ago it was suddenly impossible to connect a sensor
Reply 4 of 6, by d0k
did anyone have a problem with the serial port after upgrading windows ?
Reply 5 of 6, by evasive
We did but that is with a USB-to-serial device in windows 10. So not relevant.
You could try and see if there's any activity on the serial port with something like teraterm or any other terminal software tool.
Reply 6 of 6, by junglemontana
From that Sophos blog link:
When Microsoft first shipped this feature as an upgrade, you had to enable it. In fresh installations of Windows, it was turned on by default.
So if it was enabled by an update, maybe try disabling it? Have you tried that?