Maybe you could use a tap to thread the new holes after you drill them? Though I don't know how easy it is to acquire a tap & die set that gets you the correct threading for the standoffs...

Keep in mind that the motherboard is meant to be grounded to the case (helps discharge static for example), hence the metal surroundings on the screw holes and the existence of metal standoffs.
Not saying that you will cause problems if you use an additional non-conductive layer, many of us have done it. Just that it's not the 100% intended thing to do, as using all plastic standoffs or putting washers on every screw.

konc wrote:

Keep in mind that the motherboard is meant to be grounded to the case (helps discharge static for example), hence the metal surroundings on the screw holes and the existence of metal standoffs.
Not saying that you will cause problems if you use an additional non-conductive layer, many of us have done it. Just that it's not the 100% intended thing to do, as using all plastic standoffs or putting washers on every screw.

this is true but the motherboard will be grounded to the case through the power supply/drives/etc though. unless you specifically insulate them as well.

the threaded section of the standoffs may be long enough to have it go through the motherboard tray and put a nut on the bottom of them.

You could just use self-adhesive nylon standoffs, will be a pain if you want to remove it later though. As others mention a ground strap from the board to somewhere on the case wouldn't be bad idea.

Super_Relay wrote:

konc wrote:

Keep in mind that the motherboard is meant to be grounded to the case (helps discharge static for example), hence the metal surroundings on the screw holes and the existence of metal standoffs.
Not saying that you will cause problems if you use an additional non-conductive layer, many of us have done it. Just that it's not the 100% intended thing to do, as using all plastic standoffs or putting washers on every screw.

this is true but the motherboard will be grounded to the case through the power supply/drives/etc though. unless you specifically insulate them as well.

the threaded section of the standoffs may be long enough to have it go through the motherboard tray and put a nut on the bottom of them.

True as well and of course it can be achieved in many ways such as the separate ground mentioned. This is why it was only a "keep in mind" thing 😉

You can always use old plastic standoffs. In the past, during the AT form factor era (386, 486) many cases have only one or two brass standoffs and many holes for plastic standoffs.

You see the bottle (somehow) shaped holes in the picture?

You can fix the board with a couple of brass standoffs where it is placed appropriately and use plastic standoffs (with sawed off bottoms if required) elsewhere.