Well ... it's 386 upgraded to 486 with a 4GB CF on a UMC i/o card installed with EZ-drive and then MSDOS 6.22 on top of it. I have 128mb cards also with EZdrive and a plain vanilla MSDOS 6.22 and those don't have the problem. I must say finding a compatible CF card was a bit of a pain and for instance on a GOLDstar i/o card I got artifacts already in the bios and installing it with EZdrive didn't work. Another 2GB sandisk and a fake 4gb sandisk didn't want to play but a real maxtor 2gb drive did it's job. I am not sure if this is or can be related to my problem. I installed the current CF without probs. I have cutemouse and my cdromdriver in config.sys, disabled already.
Furthermore all I did was using memmaker. But I somehow doubt this is related.
When I boot from the msdos install disk BEFORE ezdrive can boot, the same happens.