I finally pulled the trigger on a VisionRGB-E2S fairly recently, since it was about the same price or a little more than what most eBay sellers are currently charging for the E1S, and I might as well get the one with two inputs, right?
This thing blows the old Yuan-Tech-based PEXHDCAP/SC-500N1 out of the water when it comes to VGA and DVI capture.
720x400@70Hz VGA text mode? Grabs it with no fuss.
1920x1080@60Hz? It's trying, all right, but the Mac Pro 3,1 that I crammed it in (needed to give it some kind of purpose around here!) drops frames trying to handle that.
All the screen modes an AGA Amiga can spit out, complete with on-the-fly progressive/interlaced switching? Yeah, it does all those too, but expect some vertical jailbars if you don't use a DE-15 adapter with some kind of amp (like the sort Arananet sells) and/or have the phase set dead on (and on my A4000, the ideal phase does shift a bit the longer it's been on and warmed up).
Component/YUV signals from a PS2? Color space switching is really iffy on it and VCS doesn't handle that properly, but once it's set correctly, it works very well.
I just had to adapt myself to how aspect ratio correction is NOT a job of the capture resolution, but the window resolution. You're undoubtedly going to have some ludicrously wide windows if you just try to leave the capture window at "native", and fortunately, VCS has plenty of good rescaling options so it doesn't look too bad.
Input lag is surprisingly low, too - enough that using a mouse on a captured system doesn't feel unnatural at all. I was expecting to need a splitter, but that doesn't seem to be the case - as long as I'm strictly using VCS. Having OBS open seems to delay things more noticeably even with VCS also open, which I'm not sure why it does that.
If I ever get around to building a more powerful PC for video capture, I'll test it with more demanding resolutions and refresh rates (none of my other capture devices do 1080p60, for starters), but first I'd need to find a decent Z270 motherboard to fit this 7700K into.
The other thing I need to figure out is how to capture audio and keep it synced with the VCS window the whole time, because VisionRGB cards only do video and trying to have Windows' own feature for listening in on inputs adds far, far too much latency to be usable.
As an aside, I also tested a Blackmagic Design Intensity Pro (non-4K) that I had lying around somewhere, and I almost thought the HDMI port was fried or otherwise broken because I wasn't getting anything but a black screen until I set it to capture the exact input resolution and refresh rate. That's quite a design fail if you ask me, especially for a card that can't do 1080p60.
With all that said, after having done all my research, there is one other capture device I'd like to get my hands on for testing, but at $419 new, it's quite pricey - the Magewell USB Capture DVI Plus.
It's the ONLY USB capture device I've seen that even claims to support any video mode over 60 Hz in its datasheets, also lists analog capture capabilities, and I do have some experience with their USB Capture HDMI devices at work.
PCIe cards are nice and all, but sometimes all you have is a laptop or some tiny Mac mini-esque desktop. If it works, it'd be considerably more versatile in what it could work with, all without the jank and expense of setting up an eGPU enclosure just for a capture card and needing a Thunderbolt-capable computer. I just hope USB doesn't add more latency.