Ah ha! I changed the IRQ to 7 and that fixed it, thank you very much! 😀

I just re-ran setup to try that and it looks like the defaults for Soundblaster are: IRQ: 5 IO: 220h DMA: 1

Since discovering DosBox about three years ago, I have re-played several games, all have installed and played just fine...until Eagle Eye Mysteries in London. For some reason "Sound Blaster" in the Sound Board portion of the setup doesn't work, in fact non of the options except "No Sounds" works. …