Did you mount a C drive in DOSBox?
Tried running LOADFIX before starting the game?
Tried fiddling with the xms, ems, umb settings?
Changed memsize?
Change core?
Finally, read my 60 Seconds Guide to DOSBox (and don't just read it - follow it too).
If that doesn't help, come back with details on how you mounted your C and D drives, how you did the install, how you configured sound, music etc.
Reading the aptly named README file will be a good idea too.
DOSBox 60 seconds guide | How to ask questions
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