Yes I have same experience. Playable but rather slow on my P4 2.4 GHz However I think the game runs correctly. I have original CD. It seems we only don't know the right control keys.

I'm not sure it's just a control problem. I've tried a whole bunch of key combinations to move, and nothing seems to work. I played the game years ago and I seem to remember there should be an earthquake or something like that, after which you're able to move. Has anyone played the game who could tell me if something's supposed to happen in the first scene before you're able to move?

From the game compatibility list it looks like some folks have managed to get the game running, maybe someone can suggest config settings.

I just played it under DosBox 0.63 using the original CD. I got out of the bed automatically, didn't have to press anything. You need to knock the robot into the force field at your cell door. Press C to go into combat mode, then with NumLock off use Alt + keys on numpad for different fighting moves.
I never did finish this game years ago. I think it was all of the key combinations you had to remember for fighting and interacting with the game that made me give up back then. Something else came along and got my attention and I never returned to it.

I got this problem:

The intro runs fine, speed is fine too - BUT: the 3D characters are messed up. I only see the wireframe, not the textures. Also, it crashed shortly after. I'll continue messing with the settings, see what it does.

EDIT:

Now I managed to get the graphics to look right (dynamic mode) but the game is still highly unstable. It crashed shortly after again. Speed is okay though.

Blarg, have you ever been able to solve this problem?

Im having this same strange problem. he just lays there doin nothing and i cant even get into options or the personal thing.

EDIT:
got it to work, its kinda slow but i can deal with it. it seems that either the game or dosbox doesnt like dvd drives. so i installed the game and played it with my cd burner.

Hello, I found a solution for the people who is stuck at the beginning of the game unable to move out of bed or do anything.

I copy-paste from Abandonia Forum about Bioforge:

"Attention anyone who can't get Lex to wake up at the beginning!

If he doesn't get up, this is a problem with how you've set up your sound card in the Install Program. Make sure you've got the IRQ set correctly. (For example, I use dosbox and it sets the IRQ to 7, but by default the IRQ in the install program is 5.) If the sound card is improperly set up, nothing will happen in the game.

To test this, see if there's speech going on in the intro to the game. If there's no speech, your sound card is not set up right."

I tested It and worked!

I had the same problem, and after I changed the IRQ from 5 to 7 using a Sound blaster 16 in the Install.exe, the game then worked flawlessly.

Credits to Sonicfan37 (in the page 4) from Abandonia (Thanks mate!).
http://www.abandonia.com/en/forum?url=showthread.php?t=14578