Reply 20 of 26, by pixel_workbench
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A USB mouse needs to have internal PS/2 capability to work with a PS/2 adapter. You can't just use any USB mouse that way. The general rule of thumb is if the mouse was sold with the adapter when it was new, then it should work.
I use a PS/2 keyboard and a USB optical mouse with a PS/2 adapter to minimize dependency on drivers or bios support. Generally bios support for USB input devices has been good in my experience with Socket A and newer systems, but going with PS/2 means I don't have to worry about it.