The E-Wave is about as simple as it comes for Waveblaster modules. If it doesn't work, sounds like you have a MIDI issue rather than anything specific to the E-Wave. Or do other modules work in these cases?
Re the Aztech "Washington-16", exactly which Aztech card is this? Aztech used similar names for very different cards.The FCC ID is usually diagnostic. The I38-MMSN824 was the card with proprietary WaveTide header. Other Aztech cards released as "Washington" have regular Wavetable headers.
As for the "CT2501", that's the Vibra chip on the card, not the name of the card itself (probably CT2xxx, printed on the edge of the PCB). I'm assuming it's Vibra with a regular Waveblaster connector.
In that case you're not missing anything: the Waveblaster isn't a Windows device, it's a MIDI device that is operated via the MIDI Out function of your sound card. So select SB16 MIDI Out, give it some MIDI to play and you should get wavetable coming into the SB16/Vibra mixer from the Wave input. Unmute that (if currently muted) and you should hear the output of the Waveblaster module (in this case the E-Wave).
It's worth double-checking the Aztech card, as the Vibras with CT2501 have bad MIDI bugs (both types of hanging notes and slowdowns when playing high-quality digital samples at same time as MIDI music), whereas 3rd and 4th gen Aztech cards have gloriously bug-free MIDI (and also don't suffer from the Vibra hissing/ringing sounds, and offer full WSS support), so if it can use the E-Wave, it's by far the better choice. You can keep the Vibra next to it for SB16 compatibility if you want.