Standard MAME has MIDI I/O for our working synths (including the FB-01) on Windows, Linux, and Mac hosts. -listmidi shows detected ports, -midiin specifies which of those ports goes to the MIDI IN on the emulated synth, and -midiout does the same for the output (which is more often used with our PC …

Yes, MAME supports MIDI output from the X68000 driver to a real SC55 or compatible, as long as it's a recent-ish version of MAME. https://www.youtube.com/watch?v=MTsd3n-DUwY shows Dracula X playing from MAME to an iPad running the official Roland SC55 emulator, but it works with real hardware too.

Keep in mind the usual rules for $C800 arbitration apply: you should access $CFFF to clear all cards from accessing it and then access $Cs00 where s is the slot number. At that point the $C800-$CFFE stuff for the PC Transporter is valid. Also, the Transporter's CGA is not quite standard: it programs …

Right, at the same time. We used MDA + (S)VGA + SoftICE in the game industry until Intel finally changed the chipsets to make it impossible (circa 2000, I think). Similarly, MAME's Mac driver supports multiple video cards (or multiple copies of the same one) since MacOS supported multiple heads as …

in MESS, nearly all of their IBM machines (later than the original IBM PC) are now completely broken, since most of their developers don't even seem to care about them in the slightest. On the contrary, MAME's ("MESS" was merged in over a year ago and that name is no longer used) at486 and at586 …

There is no such thing as a Universal binary of SDLMAME. You compile it customized and optimized for your own processor on your own machine. Note that the first release did not enable compiler optimizations, and between that and OpenGL mode the current builds are between 5 and 20 times faster on G5 …