Riftgarde, this idea has been discussed at lenght before in these forums. So far the answer from the developers seems to be (and please don't kill me if I have got this wrong): No - such things are better left to some frontend which can temporarily decompress the archive, run DOSBox, and recompress the archive when DOSBox exits.
And I happen to agree.
An alternative, which I use, is to get the free "Daemon Tools". It contains instructions on how to copy a full CD to an ISO-archive on the hard disk, and then how to use "Daemon Tools" to trick the OS (and DOSBox) into seeing the ISO-archive as a real CD.
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MiniMax - "The beauty of things lies in their simplicity. That's why the original Unix was beautiful. Let's keep DOSBox beautiful."
DOSBox 60 seconds guide | How to ask questions
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