Hmm you'd have to write a little program to overwrite the int 33h mouse interrupt or edit the source. And before you ask, no there will not be a config option.

Thanks!
I know its a little bit strange. But i have to deactivate it. Dosbox works very fine, but ma app...

So you may give me a hint how to write this programm?
Thanks again

uhm find a crash course on dosprogramming
more specificly find some help on assembly and intterupt vectors 😀

As you are under linux I advise you to change the source of dosbox 😀

Look at dosbox.cpp (in dosbox/src/) and look for
something like add_initfunction(Mouse_INIT)
just comment that line and the mouse is disabled.

more specificly
secprop->AddInitFunction(&MOUSE_Init);
that line.

And recompile of course.