I've had a bit of an issue for a while now with my pentium dos gaming setup.

Heres the deets :

CPU Pentium 233mmx
MOBO MSI 5148 Motherboard with 430 TX chipset
RAM 32MB of ram

The rig has about 7 cards in it (3 pci , 4 isa)

PCI
S3 Trio 64 V2/DX with 4MB or ram
3dfx Voodoo with 4mb of ram
NEC Pcx1 PowerVR card with 4mb of ram

ISA
AWE64 Gold with SIMMCON addon
Sound Blaster 16 CT2230 with socketed ASP enabled
Primax Soundstorm M16C Gravis ultrasound clone
Roland MIF IPC MPU401 BOB interface card

DRIVES
I've also got a NEC CDR 273 4x cd drive
Two 7200 rpm WD caviars : one for win95 , one for dos 6.22 and windows 3.1
1.2mb 5.25 floppy drive
1.44mb 3.5 floppy drive

So its pretty well fully laden.
Which I know doesn't really do me any favors.
But mostly everything works , except for the Sound blaster 16.
I have disabled the awe64 in DOS via the utilities.

I usually get this error , but its quite inconsistent , I've tried changing irqs and dmas etc
sometimes you can play the test sound in duke3ds setup like 10ish times before it gives the playback failed error.
Other configurations would let me run the test sound 3 times consecutively before the error.

Descent 2 will run with the sb16 and cd music in software mode , only ingame though , in the setup it refuses to play cd audio.
But if you try to disable the cd audio in game the music will keep playing anyways which is quite odd.

If you try to run Descent 2 in 3dfx mode with the cd music then the game locks up.
Ditto with tombraider.
TFX gets stuck on the second audio track.

I'm not super sure what exact conflict is causing it
the sound blaster 16 is set to 220 , 5, 1, 5
the gravis ultrasound is set to 240 7,7,7,7
awe64 is disabled
roland mif is 330H ,2/9

I've seen 8 bit i/o recovery time mentioned in posts is that something that would help?