You could get 5.25" - but not a drive that could read any PC-style 5.25" floppies.
First off, the 1541 is a single-sided drive, whereas everything newer than the first few 5150s had double-sided drives. A 486 wouldn't even know what to do with them natively (which I can confidently state as I recently accidentally got a Teac FD-55A single-sided drive that my 486 didn't recognize, it could only do DS/DD or DS/HD). But you can get around that by hooking it up externally and accessing it via dedicated software. See here:
Secondly, the electronics of a 1541 and the formatting at a physical level is completely different to anything in a PC. So even if you could attach the 1541 via a different interface, you still couldn't read or write regular PC floppies (even single-sided ones from 1981), just old C64 ones.
TLDR: great for backing up old C64 disks, useless as a replacement for a PC drive.
Instead, look for things outside of eBay. Exactly where to look differs, but whatever local Craigslist-equivalent you have would be the place to start. Sometimes they even still get given away for free - although you might end up with an FD-55A; beggars can't be choosers 😉