I don't understand much about this, but I think an ideal world would be a card that connects via riser to several ISA slots (or PCI32) and this card emulates several solutions, such as cd drives, floppy disk, hd, sound card , network, ps/2. It would be like a compatibility filter between modernity and retro. I'm afraid the costs would be high for such a complex emulation, but the costs can be amortized with demand, if many people are interested in funding a gofundme project or something like that, I think it would be feasible.
The little experience I had with things like that was creating an external emulator/synthesizer using the underside of a lenovo core2duo laptop to process VSTs, with midi inputs and outputs. The result was excellent.
Offtopic: I particularly HATE floppy disk emulators, they ruin the look, and it sucks having to choose floppy images using just that numeric display, this gave me the idea to build my own, using a real floppy drive whose head reading was replaced by a MicroSD reader, and a floppy disk with an internal microSD, and a 2" screen to choose the image to be mounted (a common and cheap display, used in Chinese MP4 players) but that during idle mode, displays a "66Mhz segment display" .