I use the Roland Sound Convas VST plugin configured for the SC-55 for all my general midi games. I don't think the SC-55 always sounds "the best" but since a lot of studios back then used the SC-55 to compose their midi tracks it does sound pretty good. I have tried timbres of heaven and the crisis font, and while they certainly can sound great with certain games they definitely don't fit every midi track IMO.
For general midi you can get really close to that with an imitation font like Deemster or Patch93s V2. I am not sure how important this is when using a sound font, but for the roland plugin I find it sounds the most accurate with a 32000 sample rate.
https://www.youtube.com/watch?v=LbVUAyDdMHs