I even surprised myself when I got some completely unexpected games to run even here on my Windows 7 x64 PC !!!
As Collector said, some games just have the installer incompatible, but the game itself is actually compatible, it happened to me with Get Medieval and Simon the Sorcerer's Pinball: I couldn't install them here on my most modern PC with Windows 7, but when I tried to launch the games directly off my Windows 98 PC via shared folder, they worked !!! I was playing them... off my Windows 98 PC on my Windows 7 PC, it was amazing.
Perhaps you can try to install the game on a virtual machine and then copy the files and folders just as they are onto Windows 10 and maybe edit some registry keys, as Collector said.
Currently assembled vintage computers I own: 11
Most important ones:
A "modded" Olivetti M4 434 S (currently broken).
An Epson El Plus 386DX running MS-DOS 6.22 (currently broken).
Celeron Coppermine 1.10GHz on an M754LMRTP motherboard