Is it a bug or is it that OpenGL/OpenGLnb do not support the autolock. Is there anyway of getting those 2 outputs to support Mouse Autolock?

I think it should work... Are you using normal Dosbox or one of the forks?
It might be a driver issue...

I'm using the one bundled with Ultimate Doom on Steam. You could be right it maybe a driver issue i'm not sure I just got the latest Nvidia update. Anyways what happens though with OpenGL and OpenGLnb it doesn't do any of the screen flicker before the game loads and the mouse just stays there. With Surface and DDraw the screen flickers and removed the mouse its so odd. Ultimate Doom is using DOSBox 0.71. so I figure that maybe the problem so now i'm going to use the latest update and see if that works.

It has been resolved I was even able to disable mouse which with version 0.74.

Please, when reporting bugs, please ALWAYS state which version you've got problems with AND always try with the latest official one, before reporting. That's true for all software, not only DOSBox;)

🤣 well thanks for the help I figured ID would have updated Ultimate Doom to 0.74. and so that is what I thought I was using. Oh well now its working and it just feels so legit making these single game packages. Following picture of what I have done. I'm sure other people have made Single Game Packs as well. What I did though is convert the bat file to a exe and I made a custom icon for it as well. This is compatible with all versions of Windows as well as monitors (fullscreen gameplay). Just click the exe file and the game starts.