Yeah - run INSTALL.EXE and choose "Soundblaster". If the game harps at you saying "Cannot detect your audio hardware" then you need to reduce your cycles. I find at 9000 or lower the games don't have any issues.
For CD versions though I don't find cycles affect the process, but as collector mentioned make sure you've mounted your CD-ROM drive and set the "-t cdrom" for it to work.
KQ4 has no speech, just music (set Adlib). KQ5 has no digital effects in the disk version (Adlib) but the CD version does. KQ6 has digital effects in both (Sound Blaster) and speech in the CD version.