Attempted to run SoftMPU on my 386/486DLC machine with a Passport MIDI PC card and says card not detected at port 330. So I'm not sure if it's because the card is incompatible, which it could be in my case (got the card on eBay) or something went wrong. No conflicts, though.
However, without the SoftMPU, LucasArts games, like Monkey Island, TIE Fighter, and Fate of Atlantis do work with the Passport MIDI PC card (Media Vision was the one that produced the card, but I cannot find info about the card, such as compatibility).
Systems from the Compaq Portable 1 to FX-6300