You should not need change anything for this CPU. Your current DX2-66 operates at 5V and needs a frontside bus of 33 MHz.
The same goes for the Pentium Overdrive that has it´s own fixed multi and a built in voltage regulator. Just plug it in and start the system.
If the current BIOS identifies the new CPU correctly is a different question. Here at "Phil`s" you can download the manual and the latest BIOS:

https://www.philscomputerlab.com/asus-vli-486sv2gx4.html

cloverskull wrote on 2022-05-28, 10:36:

Hey friends, […]
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Hey friends,

My case for this build blocks access to all the jumpers and is a real pain in the neck to put together and take apart. I'd love a bit of advice 😀 My board is a rev 2.0.

Additionally, my hands tremor a bit and setting jumpers is very difficult and I dragoon my wife into helping me and she is decidedly not a fan of this type of work. So that's basically a double whammy why I would love some assistance here and though typically I enjoy the learning experience of trial and error, eh...please help. 😀

I haven't worked much with vintage kit so all these jumpers are a bit confusing. I swapped out the 486dx66 for a POD (83mhz) and would love some advice on how to configure the jumpers. Thanks for the help.

Oh, and in case it matters, I'll be using a VLB VGA card (currently ARK1000VL and eventually a Tseng W32P) as well as some generic VLB IDE/expansion card and wish to keep full compatibility.

Thanks!

I agree with majestyk, you could just use it without changing anything. Especially when it is so troublesome for you.

With the proper jumper settings the Pentium Overdrive could run the L1 cache in WB mode. That can bring something like 15-20% performance.
But the question is if it is 100% stable then, some users have problems then with writing to a floppy disk - or other problems, depends on your other cards ....
So it is not clear, if L1 WB will work for you. So you could just take the "normal" speed gain. Especially when you do something where the FPU does the work (for example playing mp3) the gain is big.

Agree ! It should work OK w/o changing jumpers but it may display something a bit odd (my GA-486IM w/PODP5V says P24T-S @ 80Mhz, not 83mhz 🤣)

Woot! Thanks friends. I’m pumped to wrap up this build. This is excellent info!

On the offchance I wanted to try to squeeze max performance out of this CPU, just out of curiosity, what items would be changed? I’m happy with the answer everyone has given just interested to understand a bit more 😀

https://www.ultimateretro.net/en/motherboards/819#downloads has the manual and a jumper manual, as well as 5 versions of the BIOS