There have been some earlier discussions here on what the practical limits to memory expansion on the 486 were back in the day. But I won't go into detail again here. I'll make a few related points to the question:
There were likely just proprietary memory expansion slots in 486 like in 386 servers to achieve the higher specs these chips afforded. No one else cared. The 486 matured when RAM simply 1-4MB was hard to come by for the average person, except at the very end of it's life.
I believe SMP first appeared on the 486 for the x86. That could maybe make better use of more memory.
Likewise, recycled 486 systems were used to create the first beowulf cluster.
The 486 like the 386, was useful for its massively larger virtual memory capability. Perhaps useful in super-computer like situations of the day. But not so much for 1GB+ physical memory to a single program. That would have been difficult to realize in any computer spec then.
I don't believe there is any likely user of 486es back in the day that had 1GB or more memory. I think that would come during the pentium era. And more than 4GB, with the pentium pro. (obviously)
VLB probably was just consumer oriented. So I don't think anyone bothered with RAM expansion because enough expansion was available through simm sockets. I'd be pretty certain if this could be made, it would be pretty unique.