This is similar to what digger has said, maybe worded differently (for conceptualizing).
Something like DosBox could be created, for Dos, with the aim of using SBemu. One issue is native execution of code. Something similar to old QEMU's Kqemu, would be needed; this as opposed to complete CPU emulation. Some things would still need to me emulated, but you could run with fairly good speed. Then you have Win3x (and Win9x ?) support.
Although, if such contraption was built, you might as well provide the "DosBox like" emulator with its own multitasking kernel (sound server, network interfacing, etc). However, then using Sbemu would be a limiting factor, for the whole project.
I agree with digger, Sbemu is for Dos.
I think it would be better to start a project patching and developing improvements to Win3x, or develop a Dos focused replacement (mutlitasking Dos environment, with natural evolutions [like a clipboard]), in which you could run Win3x (and many other things) inside of.
But really, all of this is beyond the "current" developer potential/investment, we have available.
deomsh, from mfsn.org, has been working on adapting the HDA Win3x 16bit driver to Win9x, for some time now. I believe deomsh has a database of the different devices (and their underlying details). I think the base driver code is also available, but I'm not sure how it is licensed.
It is probably in the best interest, of all projects, to create a library for basic audio device support. You just need to build it, with the intention of supporting several projects. What we do have a lack of, is support for audio input. That "understandably" isn't a large focus.
That is what seems "to me" the next immediate consideration. Leaving Sbemu as it is, or developing a audio device library for Dos (and whatever else). crazii always wanted Sbemu improvements to also benefit Mpxplay. There was some "light" contention around a Sbemu fork, somewhat due to this. But maybe "all" could benefit from a driver library. But again, even that move may be beyond the current developer support available. And, it would mean an additional project would need stewardship.
Obviously, this isn't just a roadmap choice for Sbemu. Anyone could do this, at any point. Then it could be decided if Sbemu would benefit from using it (and any other project).