Thanks for the info, @MicroCoreLabs.
It looks like at least for maxing out the various kinds RAM, the XTMax would indeed be the way to go. And then perhaps add the PicoMEM for the mouse, game controller and network support.
To be fair, the machine that I'm upgrading, a Tandy 1000 EX, doesn't have a built-in DMA controller. It could optionally be upgraded with one, but that requires a proprietary and rare upgrade card, which I don't have. So I assume that this machine's physical floppy drive, driven by the BIOS in non-DMA mode, would likely be able to work with the emulated RAM that the PicoGUS could provide, even though it lacks DMA support.
But even then, the multiple wait states still wouldn't make it an appealing option.
@FreddyV I'm still wondering what the plans are for a Pico2-based "PicoMEM 2", and what capabilities and potential such a card would have. Likely, it would be fast enough to offer all RAM without wait states, right? I take it that you are a bit hesitant to go into detail about that, to prevent the Osbourne Effect? 😉
Anyway, I'm definitely interested in acquiring an XTMax card. Let's discuss that further in the XTMax thread.