I love the age of empires midi files. System shock is good too. Also, xcom.. btw mt-32 emulation sounds a bit naff on the sc-55.
Swampy's chest youtube channel covers a lot of gamesoundtracks in midi
https://youtu.be/l1ra0Z78iKc?si=Ute6NCSvE-q-78JR
https://youtu.be/DENSsyd2igY?si=HgS_r2CcoBTFrJ9F
https://youtu.be/BnVgoWsrSxs?si=hC6t-1huH0Q9kZAQ

I have both a MT-32 and SC-55 Mk2, and I am in the process of building a MT-32 pi midi board. I don't want to have to keep moving my two modules from my Classic Japanese Pasokon setup to either my classic PC setup or my Mac Setup. I am willing to do that with my retrotink 4k, but that just because of how stupid expensive that thing is to get a extra 2 or three of them for my other setups....

As for games I remember getting to work from DosBox(my pentium setup is only a week old so to speak) with a Roland USB->MIDI adapter.

Might and Magic 3,4,5 I don't know if they were composed with MT-32, GM, or GS in mind.
Ultima 6
Ultima 7 Parts 1&2(Exult will also output the Midi for these games)
Sam and Max
A bunch of other adventure games, and not just Sierra titles.

As a midi lover i would recommend you for now :

Tyrian or Tyrian 2000. Specially the jukebox on the setup program. A true midi masterpiece.
Z
Under a Killing Moon
System Shock
Sonic & Knuckles Collection
Blood

Screamer (not brilliant but ok)

I have Boppin', and it seems to have FM and probably MIDI support, and thanks to somebody here, I have the MIDI files, and I enjoy them. 😀

Let's try to expand the list with OpenGL games which had MIDI support. According to Gemini:

Star Wars: X-Wing:
This classic space combat simulator, developed by Totally Games and published by LucasArts, used OpenGL for rendering and MIDI for its iconic soundtrack.
Stonekeep:
Developed by Interplay Entertainment, this first-person RPG also employed OpenGL for graphics and MIDI for its music.
Street Fighter II:
This fighting game, developed and published by Capcom, utilized OpenGL for rendering and MIDI for its music.
Super Street Fighter II:
An updated version of Street Fighter II, also developed and published by Capcom, continued to use OpenGL and MIDI for its audio.
King's Quest IV: The Perils of Rosella:
This Sierra adventure game, along with others in the series, supported MIDI through its MT-32 compatibility.
Leisure Suit Larry games (various):
Similar to King's Quest, several Leisure Suit Larry games, including Leisure Suit Larry Goes Looking for Love (in Several Wrong Places) and Leisure Suit Larry III: Passionate Patti in Pursuit of the Pulsating Pectorals, used MT-32 and thus MIDI for their audio.
Space Quest III: The Pirates of Pestulon:
Another Sierra adventure game, this one also featured MT-32 support, making MIDI available.
Police Quest II: The Vengeance:
This Sierra title, part of the Police Quest series, also utilized MT-32 for its sound, including MIDI.
Operation Stealth (also known as James Bond 007: The Stealth Affair):
This game, while not a Sierra title, also supported MT-32 and thus MIDI.

Haven't played any of them -yet- 😁

Gopher666 wrote on 2025-08-19, 15:24:

Stonekeep:
employed OpenGL

Lol.

Don't use AI slop for retro stuff. Or you end up with nonsense like that.

Gopher666 wrote on 2025-08-19, 15:24:

Let's try to expand the list with OpenGL games which had MIDI support. According to Gemini: […]
Show full quote

Let's try to expand the list with OpenGL games which had MIDI support. According to Gemini:

Star Wars: X-Wing:
This classic space combat simulator, developed by Totally Games and published by LucasArts, used OpenGL for rendering and MIDI for its iconic soundtrack.
Stonekeep:
Developed by Interplay Entertainment, this first-person RPG also employed OpenGL for graphics and MIDI for its music.
Street Fighter II:
This fighting game, developed and published by Capcom, utilized OpenGL for rendering and MIDI for its music.
Super Street Fighter II:
An updated version of Street Fighter II, also developed and published by Capcom, continued to use OpenGL and MIDI for its audio.
King's Quest IV: The Perils of Rosella:
This Sierra adventure game, along with others in the series, supported MIDI through its MT-32 compatibility.
Leisure Suit Larry games (various):
Similar to King's Quest, several Leisure Suit Larry games, including Leisure Suit Larry Goes Looking for Love (in Several Wrong Places) and Leisure Suit Larry III: Passionate Patti in Pursuit of the Pulsating Pectorals, used MT-32 and thus MIDI for their audio.
Space Quest III: The Pirates of Pestulon:
Another Sierra adventure game, this one also featured MT-32 support, making MIDI available.
Police Quest II: The Vengeance:
This Sierra title, part of the Police Quest series, also utilized MT-32 for its sound, including MIDI.
Operation Stealth (also known as James Bond 007: The Stealth Affair):
This game, while not a Sierra title, also supported MT-32 and thus MIDI.

Haven't played any of them -yet- 😁

OpenGL? Absolutely nothing about "AI" is intelligent, and most of the time it comes up with nonsensical garbage. To research a topic just do it manually.

The only OpenGL + MIDI game I do know of is Hexen II.

Fuck that AI slop above this post. Should be a bannable offense for creators of 'list' threads to push misinformation tbh imo

Hey, be nice! It just goes to show computer bots can never replace thinking humans. I started, but no one seemed to have anything to contribute to, a topic a few weeks back trying to ascertain what games were designed for what MIDI device and/or standard; this one is broader, and a list encompassing MIDI-supporting games would be near endless, but if we narrowed it down into its elements that could get us somewhere helpful.