Not sure if anybody else has an X45, but in case it may help someone...

After selecting the joystick map 'Single 4-axis, 4-button joystick (with rudder and throttle),' my shortcuts ceased to run, giving an error about initializing 'JoystickController.' And also mentioned axis T. (Sorry, don't still have the full text).

I realized from the complete error that it was attempting to map axes X,Y,T,R while my drivers (Dhauzimmer 2.105b) have the axes listed as X,Y,Z,R. Simply opening joy3.map and changing the line:

analog.4 = A.analog.T

to

analog.4 = A.analog.Z

fixed the problem, and has me with nearly full HOTAS functionality even in these old games.

Thanks guys.