is there anyway to trigger it without holding ALT + F12?
DOSBox doesn't natively support that feature, but here is a round-about way of doing it.
If you create a custom "Mapper.txt" key mapper file for DOSBox, and edit/change this:
1hand_speedlock "key 293 mod2"
...to this:
1hand_speedlock "key 293 mod2 hold"
...that will allow you to press ALT+F12 once to enable "turbo" mode.
Although, note that when using this method, turbo mode will be active for the ENTIRE time that the current DOSBox session is running (i.e. there is no way to toggle turbo mode off again without shutting down and then restarting DOSBox).