@filipetolhuizen: Yah, I installed the latest Liveware drivers. Same result. I'm going to be changing to an ISA sound card for DOS applications, so this should not (in theory) be the issue. I've found a number of problems with Dos emulation and program compatibility with this particular Sound Blaster card.
@VirtuaIceMan: Unfortunately, I was not receiving an error or "bong" noise indicating an error from Windows. The entire system would lock up (unable to access task manager, return to Windows Desktop, zero feedback from the machine via mouse and keyboard, etc.), requiring a hard boot to restart the system. Thank you for the idea, though.