Originally posted this in the wrong forum, was told it belongs here

I have a Tandy 2500 SX/33 (33mhz 386sx) which I'm using for DOS gaming, everything's been good except no matter what CD-ROM device driver I load, the system reboots immediately, regardless if there is even a CD-ROM plugged into the IDE port or not. My OS is DOS 6.22.

This system has a single IDE port on the motherboard, it's BIOS has no provision for a CD-ROM (but I think that shouldn't matter?). This occurs no matter what I specify for the "D:" drive in the BIOS (choice of Auto or None).

Here's a video of the problem:

https://www.youtube.com/watch?v=ooGhuJjXeCE

Here's my config.sys (CD-ROM driver REM'd out so I can boot):

1DEVICE=C:\DOS\HIMEM.SYS
2DEVICE=C:\DOS\EMM386.EXE RAM
3BUFFERS=15,0
4FILES=40
5DOS=UMB
6LASTDRIVE=E
7FCBS=4,0
8DEVICEHIGH /L:1,25904 =C:\APPS\VIBRA16\DRV\VIBRA16.SYS /UNIT=0 /BLASTER=A:220 I:5 D:1 H:5
9DEVICEHIGH /L:1,10416 =C:\APPS\VIBRA16\DRV\CTMMSYS.SYS
10REM ** FILES=30
11DEVICEHIGH /L:1,12048 =C:\DOS\SETVER.EXE
12REM DEVICEHIGH=C:\DOS\CDROMDRV.SYS /d:mscd001
13DOS=HIGH

And autoexec.bat:

1@ECHO OFF
2SET SOUND=C:\APPS\VIBRA16
3SET BLASTER=A220 I5 D1 H5 P330 T6
4SET MIDI=SYNTH:1 MAP:E
5C:\APPS\VIBRA16\DIAGNOSE /S
6C:\APPS\VIBRA16\MIXERSET /P /Q
7loadhigh C:\DOS\SMARTDRV.EXE 
8loadhigh c:\dos\mscdex.exe /d:mscd001
9c:\dos\ctmouse.exe /3
10PROMPT $p$g
11PATH C:\APPS;C:\DOS
12SET TEMP=C:\TEMP
13SET DIRCMD=/o:gne
14echo.

Apologies for the messy files but it's a pretty new install and I just let memmaker do it's thing. Does anyone have any idea what's going on here? I'm completely stumped.

EDIT: I've tried five or six different CD drivers (Oak, LG,etc) all with the exact same effect.

The only other problem I'm having with this machine is this error Creative's diagnose.exe gives me when I run it:

The sound card I have installed is a CT2800 Vibra16 (no IDE), despite giving this error it works fine. Maybe related?

EDIT2: The problem occurs even with config/autoexec files that are completely empty save for the driver and mscdex.