I've been battling with this myself for a long time now. Very frustrated as I NEED to finish the trilogy!
I've followed the steps outlined in previous posts (on this board and others) including the VDMSound routine:
1) Run setup (with and without VDMS support)
2) Selected pure "Sound Blaster" type card
3) Finalised the installation following game setup instructions
4) Selected DOS and later Windows type game
5) Went to game directory and make right-click on "runmain.exe" file and selected melody icon "Run with VDMS"
6) Made default settings by pressing "Next" and then "Finish" button
7) Right-clicked on newly created VDMS shortcut for this file
8 ) Chose "Properties" item and enabled "Low-level CD-ROM Support" and click "Apply"
Now, aparently, this is supposed to work, and to a degree it did. But I still get the exact same problem as chris1990 outlined.
It seems as if it's trying to read the music and the voice dialogue from the CD (which isn't there) and just skipping.
When I quit out there was this error message:
(28 ) IO error with ANYTALK.TLK (11) - exiting
HELP! I'm damn desperate!