Have you considered using post-process antialiasing?

I've tried this. First if you want MSAA to work you need to stick to integer scales of the game's resolution. 1024x768,2048x1536,3072x2304, etc... Then it will work very nicely (for the most part, it will temporarily glitch out during zoom animation):

If you use the non-integer scale in your screenshot, which will also badly affect scrolling (if the entire background shimmering when you move, this is why), then your best choice is what I mentioned, post-processing AA. Here's ReShade's SMAA shader:

Here's the same scene with no antialiasing:

Thanks for looking into this, however using integer scale resolution (2048x1536) didn't change anything for me.

Could it be caused by the Windowed mode? Your screenshot seems to be fullscreen, however I'm trying to work with a window. I leave the game's config in Fullscreen mode, and I set dgVoodoo to force windowed.

Make sure you're not forcing any sort of texture filtering.

It's the resolution forcing.
DO NOT use it with 2D elements-heavy game like Sacred 😜

lowenz wrote:

It's the resolution forcing.
DO NOT use it with 2D elements-heavy game like Sacred 😜

Uh? It works pretty well in this case and it makes for a noticeable quality increase for 3D models.

Pretty well ending up with a "fence" of squares/tiles.

lowenz wrote:

Pretty well ending up with a "fence" of squares/tiles.

As mentioned, only in non-integer ratio scales and then only if you force antialiasing. See the screenshots I posted.

The "and" is not true.
Sacred Gold @1440x1080 (from native 1024x768), with NO MSAA, start screen:

That's only the title screen and the character selection screen though.