The only point of OEM PCs is being able to sell/purchase cost-effective products. Where I come from, these are considered inferior to semi-OEMs/PC builders where you can choose the components yourself. The obvious cons are: BIOSes are often feature-restricted (less for a customer to break = less tech support costs), case, PSU and motherboard designs are intentionally less interchangeable (so you could only seek replacement at the OEM's office, and not any computer store), and unwanted bloatware.
How to start an OEM operation:
1. Choose a catchy company name;
2. Rent a warehouse and a couple of offices, hire guys that can quickly build PCs;
3. Visit China or Taiwan, make a deal with manufacturers on volume-selling you some cost-effective parts;
4. While you're at it, find a decent PC case factory and make another deal for selling some case models exclusively to you;
5. ???
6. PROFIT
So if you can give some components a real purpose - why bother? I'd only preserve the weird stuff - like Packard Bell Corner Desktop or Compaq iPAQ...
On the other hand, if you have fond memories of a particular computer model, or if you like the idea behind its set of components (if they are exeptionally balanced performance-wise, or maybe they arrange in a theme you dig) - sure, why not. I once built a retro PC with all components manufactured strictly in late 1996 😀 Just for theme's sake, and only because I was unable to find a stock (semi-)OEM one from this exact time period.