I started doing testing on my Asus P4C800-E Deluxe again after nearly two years of not doing anything with it, and I noticed under Windows XP that after I use HWINFO to probe for system sensors and try to restart the system, the board gets stuck at POST code do. I am running XP Pro SP3 fully-updated, default services, latest Intel chipset drivers (not that they matter much), and have accounted for effectively all the hardware (with both the motherboard and video cards tested being fully-recapped).
I did not have any issues with HWINFO back when I tested this board two years ago, and sure enough, the version from around the time I was doing testing on the board (v7.22) worked without issue. I then went version-by-version to find the culprit - v7.40, the first version to display this behavior. Turning-off SMBus support does prevent the issue from occurring, but I'd think that's less than ideal.
I generated reports and then generated debug files from opening in "sensors-only" mode for 10 seconds for 7.36, 7.40, and the latest 8.24, both with and without SMBus support enabled and with resets in-between, attached to this post.