Bad install? as that's a preferable answer to hardware issue
I've played it on a Dx2/66 up to a P3 1Ghz without disabling anything.

Which hard issue should i go after? Hdd maybe? Don't think it's a bad install because I've tried different sources of the game with the same result.

If the caches have to disabled to function correctly, maybe there is a fault in one of the cache ICs? Or maybe your BIOS has some other cache related settings?

Starting to suspect of the dual boot (Dos 6.22/win98) via plop recently installed, I started a different fresh new hdd with pure dos only and guess what... The game crashed again. In some messages i could catch from a picture like the one i've uploaded says something like DOS4GW Professional error. Any clue on how to fix it? Or i've just to change my motherboard?

Just for the sake of it: can you run memtest86 on your machine, to check if all RAM and cache is good?

Well, i've ran a memtest86 as you suggested. When it started to find errors the program freaked out in a myriad of colors. So... The problem is the cache memory. Any way to fix issues like that?

Another run of memtest86 and i've been able to take this picture and now my question is: the errors are from the caches or one of the 32mb simm edo rams?