Sure can, just do it the same way Gog does by using command line options and a batch file/shortcut to start the game fullscreen with whatever options you've already set. For example, put your game and a dosbox distribution into the same folder, then set a shortcut to start like this:
dosbox.exe -conf game.conf -noconsole -c exit
You can use the default dosbox.conf or make your own (game.conf) specific version. Consult the wiki or see sticky posts for manual config editing. This way you can setup a "machine" config that matches the period of the game and plays it exactly the way it was intended. Then just zip it all up and share as needed.